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NIAS in Plastic Food Contact Materials

Introduction Plastics are more than complex mixture of polymers in which non intentionally products are also added which is well known as NIAS (non-intentionally added substance). Impurities, degrade products and byproducts can be formed during reaction and are well known examples of NIAS products. Plastic chemicals such as bisphenol and phthalates have been detected in the US for more than 90%. Indeed plastics chemicals are considered as harmful products for humans as well as for nature. A disruption of chemicals of the endocrine system contributes to a wide range of adverse health effects to humans which links to exposure of BIS and phthalates. Why it matters? Health Risks: Notably, BIS and phthalates also act as MDCs (Metabolism disrupting chemicals). MDCs promote obesity, type 2 diabetes or other metabolic disorders basically increase in non communicable diseases. As far as it concerns, metabolic disruption can be mediated via nuclear receptors. Plastic p...

Plastics and Toxic Chemical Mixtures: Understanding NIAS and the Emerging Health Concerns

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  Introduction Plastics are not just polymers but far more complex, they are a sophisticated blend of additives, byproducts, and impurities. These include non-intentionally added substances (NIAS), a term describing impurities, degradation products, and reaction byproducts unintentionally present in plastic materials. Increasingly, science reveals that the chemicals in plastics such as bisphenols and phthalates pose significant health concerns for both humans and the environment. In fact, in the United States, bisphenol and phthalate compounds have been detected in over 90% of people tested .[ LINK ]   This report explains why understanding the composition and toxicity of plastics is crucial, especially those used in food contact materials, and how advanced analytical approaches like PLS regression support this effort.   Why It Matters   1. Ubiquity of Harmful Chemicals in Plastics   Plastics are a main source of exposure to endocrine-disrupting chemicals (ED...